van de Lande LS, Caron CJJM, Pluijmers BI, Joosten KFM, Streppel M, Dunaway DJ, Koudstaal MJ, Padwa BL.
Dysphagia. 2018 Apr;33(2):234-242.
In a studies involved three major craniofacial units, 13.5% of the 755 patients with craniofacial microsomia were diagnosed with swallowing difficulties. There was a relation between the severity of the underdevelopment of the mandible and the ability to form an appropriate bolus. The authors recommend routine screening for swallowing difficulties by a speech and language therapist in all patients with craniofacial microsomia.
Renkema RW, Caron CJJM, Wolvius EB, Dunaway DJ, Forrest CR, Padwa BL, Koudstaal MJ.
Int J Oral Maxillofac Surg. 2018 Jan;47(1):27-34.
In this systematic review, 16 papers were included. The most common anomalies of the central nervous system were neural tube defects, corpus callosum agenesis or hypoplasia, intracranial lipoma, Chiari malformations, hydrocephalus, ventriculomegaly, and cerebral hypoplasia. The prevalence of these anomalies varies from 2% to 69%. Prevalence of intellectual disability, language and speech developmental delay and neuropsychomotor delay varies between 8% and 73%.
Renkema RW, Caron CJJM, Mathijssen IMJ, Wolvius EB, Dunaway DJ, Forrest CR, Padwa BL, Koudstaal MJ.
Int J Oral Maxillofac Surg. 2017 Oct;46(10):1319-1329
Thirty-one papers were included in this systematic review. The most often encountered vertebral anomalies are hemivertebrae, block vertebrae, scoliosis/kyphoscoliosis, and spina bifida. The prevalence ranges from 8% to 79%.
Caron CJJM, Pluijmers BI, Maas BDPJ, Klazen YP, Katz ES, Abel F, van der Schroeff MP, Mathijssen IMJ, Dunaway DJ, Mills C, Gill DS, Bulstrode N, Padwa BL, Wolvius EB, Joosten KFM, Koudstaal MJ.
Int J Oral Maxillofac Surg. 2017 Oct;46(10):1330-1337.
A total of 755 patients with craniofacial microsomia were included from three craniofacial centers. In 17.6% of the patients, obstructive sleep apnoea was diagnosed. This concerned particularly patients with a more severe underdevelopment of the mandible and the patients in whom the mandible is affected on both sides. Treatment of the obstructive sleep apnoea should be individualized and based on clinical symptoms, the severity of the deformity, and comorbidities.