Research neurofibromatosis

Endoscopic Third Ventriculostomy in Patients with Neurofibromatosis Type 1: A Multicenter International Experience.

Roth J, Ber R, Wisoff JH, Hidalgo ET, Limbrick DD, Berger DS, Thomale UW, Schulz M, Cinalli G, Santoro C, Constantini S.

World Neurosurg. 2017 Nov;107:623-629.

Patients with neurofibromatosis type 1 can develop hydrocephalus that requires treatment. One option for treatment is endoscopic third ventriculostomy (ETV). This paper present the result of that treatment in 42 patients. ETV failed in 6 patients within 1 months, in 3 patients within 9 months, and in 1 patient within 4 years. ETV was successful in 32 patients with a mean follow-up period of 59 months (ranging from 4 months to 15 years). Conclusion: ETV is a safe treatment for selected patients with neurofibromatosis type 1 and obstructive hydrocephalus.