Clinical guidelines

Craniofacial microsomia

ERN CRANIO has developed a European guideline on craniofacial microsomia.

Ahead of print publication in the Journal of Craniofacial Surgery, more information can be found here:

The Need for a Guideline to Impact Patients Outcome in Craniofacial Microsomia

European Guideline Craniofacial microsomia

A patient version of the developed guideline is also in development.


ERN CRANIO endorses the Dutch guideline for craniosynostosis (Published in 2015). 

Cleft lip/palate

ERN CRANIO endorses the Dutch guideline for 'schisis' (Published in 2017) [The term “schisis” in Dutch encompasses all types of facial clefts, most commonly clefts of the lip and/or palate]

In 2018, this Dutch guideline was translated into English which was funded by ERN CRANIO: English version of the Dutch guideline for 'schisis' 

[The type of cleft is clearly specified where needed as there is no direct English translation for the Dutch word 'schisis']. Click here for more information on this translation work.